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This Concept Map, created with IHMC CmapTools, has information related to: The Immune System Group 3, inflammation signs heat, Internal Defenses 2nd line of defense consists of inflammation, Surface Barriers 1st line of defense found line all oxposed body cavities and organs, Internal Defenses 2nd line of defense consists of cells, neutrofils enter blood from bone marrow caused by release of leukocytosis inducing factor, engulf and destroy pathogens through attachment of antibodies or complements to phagocyte receptors, neutrofils enter blood from bone marrow leads to margination leukocytes cling to capillary walls, inflammation function promotes healing, cells type Natural Killer Cells (lymphocytes), antimicrobial proteins acts through complement system, phagocytes function engulf and destroy pathogens, inflammation signs swelling, Surface Barriers 1st line of defense includes keratin, Innate type Surface Barriers 1st line of defense, classical acts through antibodies, inflammation steps neutrofils enter blood from bone marrow, Surface Barriers 1st line of defense includes lysozymes, Surface Barriers 1st line of defense includes skin acidity, Natural Killer Cells (lymphocytes) function nonspecifically kill virus-infected and malignant cells, margination leukocytes cling to capillary walls leads to diapedesis passage of leukocytes through capillary walls